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6K0Y

Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Antibody Heavy Chainpolymer21823276.01Homo sapiens (Human)
2B
(B)
Antibody Light Chainpolymer21423447.11Homo sapiens (Human)
3C
(C)
Programmed cell death protein 1polymer14315954.71UniProt (Q15116)
Pfam (PF07686)
Homo sapiens (Human)hPD-1
4D, E, F, G
(A, B, C)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
5H, I, J
(A, B, C)
waterwater18.0492Chemie (HOH)
Sequence modifications
C: 25 - 167 (UniProt: Q15116)
PDBExternal DatabaseDetails
Ser 93Cys 93engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight62677.8
Non-Polymers*Number of molecules4
Total formula weight248.3
All*Total formula weight62926.0
*Water molecules are not included.

227111

PDB entries from 2024-11-06

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