6JTG
Structural insights into G domain dimerization and pathogenic mutations of OPA1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dynamin-like 120 kDa protein, mitochondrial,OPA1 protein | polymer | 350 | 38942.3 | 1 | UniProt (O60313) UniProt (Q6PEK6) Pfam (PF00350) In PDB | Homo sapiens (Human) | Optic atrophy protein 1 |
| 2 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | A | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 1 | Chemie (BEF) | |||
| 5 | A | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 6 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A: 1 - 309 (UniProt: O60313)
A: 328 - 350 (UniProt: Q6PEK6)
| PDB | External Database | Details |
|---|---|---|
| Phe 310 | - | linker |
| Asn 311 | - | linker |
| Leu 312 | - | linker |
| Glu 313 | - | linker |
| Thr 314 | - | linker |
| Glu 315 | - | linker |
| Trp 316 | - | linker |
| Lys 317 | - | linker |
| Asn 318 | - | linker |
| Gly 319 | - | linker |
| Ser 320 | - | linker |
| Gly 321 | - | linker |
| Ser 322 | - | linker |
| Gly 323 | - | linker |
| Ser 324 | - | linker |
| Gly 325 | - | linker |
| Gly 326 | - | linker |
| Ser 327 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38942.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 572.6 | |
| All* | Total formula weight | 39514.9 |
