6JTA
Crystal Structure of D464A L465A mutant of FGAM Synthetase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Phosphoribosylformylglycinamidine synthase | polymer | 1303 | 142351.2 | 1 | UniProt (A0A0D6F9Y3) Pfam (PF18076) Pfam (PF18072) Pfam (PF02769) Pfam (PF22689) Pfam (PF13507) UniProt (by SIFTS) (P74881) In PDB | Salmonella typhimurium | FGAMS,Formylglycinamide ribonucleotide amidotransferase,FGAR-AT |
2 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) | |||
3 | A | GLUTAMINE | non-polymer | 146.1 | 1 | Chemie (GLN) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 12 | Chemie (GOL) | |||
5 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 23 | Chemie (EDO) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
7 | A | SULFATE ION | non-polymer | 96.1 | 18 | Chemie (SO4) | |||
8 | water | water | 18.0 | 1204 | Chemie (HOH) |
Sequence modifications
A: 1 - 1295 (UniProt: A0A0D6F9Y3)
PDB | External Database | Details |
---|---|---|
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Ala 464 | Asp 464 | engineered mutation |
Ala 465 | Leu 465 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 142351.2 | |
Non-Polymers* | Number of molecules | 58 |
Total formula weight | 4908.1 | |
All* | Total formula weight | 147259.3 |