6JJO

Crystal structure of the DegP dodecamer with a modulator

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Periplasmic serine endoprotease DegP	polymer	469	49155.5	6	UniProt (P0C0V0) Pfam (PF13365) Pfam (PF00595) In PDB	Escherichia coli K-12	Heat shock protein DegP,Protease Do
2	G, M, H, N, I...	TMB-CYRKL modulator	polymer	5	683.9	12		Escherichia coli

Sequence modifications

A, B, C, D, E, F: 1 - 448 (UniProt: P0C0V0)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ala 210	Ser 236	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	303139.2
All*	Total formula weight	303139.2

*Water molecules are not included.