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6JJO

Crystal structure of the DegP dodecamer with a modulator

Functional Information from GO Data
ChainGOidnamespacecontents
A0004175molecular_functionendopeptidase activity
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005886cellular_componentplasma membrane
A0006457biological_processprotein folding
A0006508biological_processproteolysis
A0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
A0006979biological_processresponse to oxidative stress
A0008233molecular_functionpeptidase activity
A0008236molecular_functionserine-type peptidase activity
A0009266biological_processresponse to temperature stimulus
A0009408biological_processresponse to heat
A0030288cellular_componentouter membrane-bounded periplasmic space
A0042597cellular_componentperiplasmic space
A0042802molecular_functionidentical protein binding
A0061077biological_processchaperone-mediated protein folding
B0004175molecular_functionendopeptidase activity
B0004252molecular_functionserine-type endopeptidase activity
B0005515molecular_functionprotein binding
B0005886cellular_componentplasma membrane
B0006457biological_processprotein folding
B0006508biological_processproteolysis
B0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
B0006979biological_processresponse to oxidative stress
B0008233molecular_functionpeptidase activity
B0008236molecular_functionserine-type peptidase activity
B0009266biological_processresponse to temperature stimulus
B0009408biological_processresponse to heat
B0030288cellular_componentouter membrane-bounded periplasmic space
B0042597cellular_componentperiplasmic space
B0042802molecular_functionidentical protein binding
B0061077biological_processchaperone-mediated protein folding
C0004175molecular_functionendopeptidase activity
C0004252molecular_functionserine-type endopeptidase activity
C0005515molecular_functionprotein binding
C0005886cellular_componentplasma membrane
C0006457biological_processprotein folding
C0006508biological_processproteolysis
C0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
C0006979biological_processresponse to oxidative stress
C0008233molecular_functionpeptidase activity
C0008236molecular_functionserine-type peptidase activity
C0009266biological_processresponse to temperature stimulus
C0009408biological_processresponse to heat
C0030288cellular_componentouter membrane-bounded periplasmic space
C0042597cellular_componentperiplasmic space
C0042802molecular_functionidentical protein binding
C0061077biological_processchaperone-mediated protein folding
D0004175molecular_functionendopeptidase activity
D0004252molecular_functionserine-type endopeptidase activity
D0005515molecular_functionprotein binding
D0005886cellular_componentplasma membrane
D0006457biological_processprotein folding
D0006508biological_processproteolysis
D0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
D0006979biological_processresponse to oxidative stress
D0008233molecular_functionpeptidase activity
D0008236molecular_functionserine-type peptidase activity
D0009266biological_processresponse to temperature stimulus
D0009408biological_processresponse to heat
D0030288cellular_componentouter membrane-bounded periplasmic space
D0042597cellular_componentperiplasmic space
D0042802molecular_functionidentical protein binding
D0061077biological_processchaperone-mediated protein folding
E0004175molecular_functionendopeptidase activity
E0004252molecular_functionserine-type endopeptidase activity
E0005515molecular_functionprotein binding
E0005886cellular_componentplasma membrane
E0006457biological_processprotein folding
E0006508biological_processproteolysis
E0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
E0006979biological_processresponse to oxidative stress
E0008233molecular_functionpeptidase activity
E0008236molecular_functionserine-type peptidase activity
E0009266biological_processresponse to temperature stimulus
E0009408biological_processresponse to heat
E0030288cellular_componentouter membrane-bounded periplasmic space
E0042597cellular_componentperiplasmic space
E0042802molecular_functionidentical protein binding
E0061077biological_processchaperone-mediated protein folding
F0004175molecular_functionendopeptidase activity
F0004252molecular_functionserine-type endopeptidase activity
F0005515molecular_functionprotein binding
F0005886cellular_componentplasma membrane
F0006457biological_processprotein folding
F0006508biological_processproteolysis
F0006515biological_processprotein quality control for misfolded or incompletely synthesized proteins
F0006979biological_processresponse to oxidative stress
F0008233molecular_functionpeptidase activity
F0008236molecular_functionserine-type peptidase activity
F0009266biological_processresponse to temperature stimulus
F0009408biological_processresponse to heat
F0030288cellular_componentouter membrane-bounded periplasmic space
F0042597cellular_componentperiplasmic space
F0042802molecular_functionidentical protein binding
F0061077biological_processchaperone-mediated protein folding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues18
DetailsACT_SITE: Charge relay system => ECO:0000269|PubMed:20581825
ChainResidueDetails
AHIS105
DHIS105
DASP135
DALA210
EHIS105
EASP135
EALA210
FHIS105
FASP135
FALA210
AASP135
AALA210
BHIS105
BASP135
BALA210
CHIS105
CASP135
CALA210

site_idSWS_FT_FI2
Number of Residues36
DetailsBINDING:
ChainResidueDetails
AGLU32
BGLY208
BTHR226
BLEU265
CGLU32
CHIS105
CASP135
CGLY208
CTHR226
CLEU265
DGLU32
AHIS105
DHIS105
DASP135
DGLY208
DTHR226
DLEU265
EGLU32
EHIS105
EASP135
EGLY208
ETHR226
AASP135
ELEU265
FGLU32
FHIS105
FASP135
FGLY208
FTHR226
FLEU265
AGLY208
ATHR226
ALEU265
BGLU32
BHIS105
BASP135

222036

PDB entries from 2024-07-03

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