6JE9
Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CRISPR-associated endonuclease Cas9 | polymer | 1092 | 125935.2 | 2 | UniProt (C9X1G5) Pfam (PF13395) Pfam (PF18541) In PDB | Neisseria meningitidis 8013 | |
2 | B, D | sgRNA | polymer | 135 | 43059.4 | 2 | synthetic construct | ||
3 | E, F | AcrIIC3 | polymer | 117 | 13457.4 | 2 | UniProt (A0A3E2QDI5) UniProt (by SIFTS) (A0A425B395) In PDB | Neisseria meningitidis 8013 |
Sequence modifications
A, C: 1 - 1082 (UniProt: C9X1G5)
E, F: 1 - 116 (UniProt: A0A3E2QDI5)
PDB | External Database | Details |
---|---|---|
Ser 1083 | - | expression tag |
Glu 1084 | - | expression tag |
His 1085 | - | expression tag |
His 1086 | - | expression tag |
His 1087 | - | expression tag |
His 1088 | - | expression tag |
His 1089 | - | expression tag |
His 1090 | - | expression tag |
His 1091 | - | expression tag |
His 1092 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 364903.8 | |
All* | Total formula weight | 364903.8 |