6JE9
Crystal structure of Nme1Cas9-sgRNA dimer mediated by double protein inhibitor AcrIIC3 monomers
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003677 | molecular_function | DNA binding |
A | 0003723 | molecular_function | RNA binding |
A | 0004519 | molecular_function | endonuclease activity |
A | 0043571 | biological_process | maintenance of CRISPR repeat elements |
A | 0046872 | molecular_function | metal ion binding |
A | 0051607 | biological_process | defense response to virus |
C | 0003676 | molecular_function | nucleic acid binding |
C | 0003677 | molecular_function | DNA binding |
C | 0003723 | molecular_function | RNA binding |
C | 0004519 | molecular_function | endonuclease activity |
C | 0043571 | biological_process | maintenance of CRISPR repeat elements |
C | 0046872 | molecular_function | metal ion binding |
C | 0051607 | biological_process | defense response to virus |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: For RuvC-like nuclease domain => ECO:0000255|HAMAP-Rule:MF_01480 |
Chain | Residue | Details |
A | ASP16 | |
C | ASP16 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton acceptor for HNH nuclease domain => ECO:0000255|HAMAP-Rule:MF_01480 |
Chain | Residue | Details |
A | HIS588 | |
C | HIS588 |
site_id | SWS_FT_FI3 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01480 |
Chain | Residue | Details |
A | ASP16 | |
A | GLU504 | |
A | GLU508 | |
A | HIS723 | |
C | ASP16 | |
C | GLU504 | |
C | GLU508 | |
C | HIS723 |