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6J6L

Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Ryanodine receptor 2polymer19822048.72UniProt (E9Q401)
Pfam (PF00622)
Mus musculus (Mouse)RyR2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,Type 2 ryanodine receptor
2C, D, E, F, G...
(A, B)
ISOPROPYL ALCOHOLnon-polymer60.16Chemie (IPA)
3I, J
(A, B)
waterwater18.0508Chemie (HOH)
Sequence modifications
A, B: 650 - 844 (UniProt: E9Q401)
PDBExternal DatabaseDetails
Ser -2-expression tag
Asn -1-expression tag
Ala 0-expression tag
Phe 784Ile 784engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44097.4
Non-Polymers*Number of molecules6
Total formula weight360.6
All*Total formula weight44458.0
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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