6J10
Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Capsid protein | polymer | 149 | 16692.1 | 6 | UniProt (P03147) Pfam (PF00906) | Hepatitis B virus genotype D subtype adw (HBV) | Core protein |
| 2 | G, H, I (B, D, F) | 6-cyclohexyl-4-methyl-1-oxidanyl-pyridin-2-one | non-polymer | 207.3 | 3 | Chemie (B4O) | |||
| 3 | J, K, L, M, N... (A, B, C, D, E...) | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 149 (UniProt: P03147)
| PDB | External Database | Details |
|---|---|---|
| Ala 132 | Tyr 132 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100152.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 621.8 | |
| All* | Total formula weight | 100774.2 |
