6IYB

Structure of human ORP1 ANK - Rab7 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Ras-related protein Rab-7a	polymer	199	22536.6	2	UniProt (P51149) Pfam (PF00071)	Homo sapiens (Human)
2	B, D (B, D)	Oxysterol-binding protein-related protein 1	polymer	154	17011.2	2	UniProt (Q9BXW6) Pfam (PF12796)	Homo sapiens (Human)	OSBP-related protein 1
3	E, G (A, C)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG) PubChem (888)
4	F, H (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466)
5	I, J, K, L (A, B, C, D)	water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, C: 2 - 195 (UniProt: P51149)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Ala -2	-	expression tag
Met -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Leu 67	Gln 67	engineered mutation
-	Leu 73	deletion

B, D: 5 - 152 (UniProt: Q9BXW6)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 1	-	expression tag
Met 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	79095.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1095.0
All*	Total formula weight	80190.6

*Water molecules are not included.