6IYB

Structure of human ORP1 ANK - Rab7 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Ras-related protein Rab-7a	polymer	199	22536.6	2	UniProt (P51149) Pfam (PF00071) In PDB	Homo sapiens (Human)
2	B, D	Oxysterol-binding protein-related protein 1	polymer	154	17011.2	2	UniProt (Q9BXW6) Pfam (PF12796) In PDB	Homo sapiens (Human)	OSBP-related protein 1
3	A, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A, C	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
5		water	water		18.0	334	Chemie (HOH)

Sequence modifications

A, C: 2 - 195 (UniProt: P51149)

PDB	External Database	Details
Gly -4	-	expression tag
Ser -3	-	expression tag
Ala -2	-	expression tag
Met -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Leu 67	Gln 67	engineered mutation
-	Leu 73	deletion

B, D: 5 - 152 (UniProt: Q9BXW6)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 1	-	expression tag
Met 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	79095.7
Non-Polymers*	Number of molecules	4
	Total formula weight	1095.0
All*	Total formula weight	80190.6

*Water molecules are not included.