6IOL

Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (I, J, K, L, M...)	Multidrug resistance protein MexA	polymer	362	38789.7	6	UniProt (P52477) Pfam (PF00529) Pfam (PF16576)	Pseudomonas aeruginosa
2	G, H, I (A, B, C)	Outer membrane protein OprM	polymer	474	51737.6	3	UniProt (Q51487) Pfam (PF02321)	Pseudomonas aeruginosa PAO1
3	J, K, L (F, G, E)	Multidrug resistance protein MexB	polymer	1054	113948.3	3	UniProt (P52002) Pfam (PF00873)	Pseudomonas aeruginosa PAO1	Multidrug-efflux transporter MexB

Sequence modifications

I, J, K, L, M, N: 2 - 360 (UniProt: P52477)

PDB	External Database	Details
Gly -1	-	expression tag
Ala 0	-	expression tag
Met 1	-	expression tag

A, B, C: 1 - 468 (UniProt: Q51487)

PDB	External Database	Details
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag
His 472	-	expression tag
His 473	-	expression tag
His 474	-	expression tag

F, G, E: 1 - 1046 (UniProt: P52002)

PDB	External Database	Details
Leu 1047	-	expression tag
Glu 1048	-	expression tag
His 1049	-	expression tag
His 1050	-	expression tag
His 1051	-	expression tag
His 1052	-	expression tag
His 1053	-	expression tag
His 1054	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	729795.8
All*	Total formula weight	729795.8

*Water molecules are not included.