6IF3
Complex structure of Rab35 and its effector ACAP2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 | polymer | 174 | 19000.1 | 1 | UniProt (Q15057) Pfam (PF12796) | Homo sapiens (Human) | Centaurin-beta-2,Cnt-b2 |
| 2 | B (B) | Ras-related protein Rab-35 | polymer | 186 | 21095.9 | 1 | UniProt (Q15286) Pfam (PF00071) | Homo sapiens (Human) | GTP-binding protein RAY,Ras-related protein Rab-1C |
| 3 | C (B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 4 | D (B) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A: 601 - 770 (UniProt: Q15057)
B: 1 - 180 (UniProt: Q15286)
| PDB | External Database | Details |
|---|---|---|
| Gly 597 | - | expression tag |
| Pro 598 | - | expression tag |
| Gly 599 | - | expression tag |
| Ser 600 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
| Leu 67 | Gln 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40096.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 40643.5 |
