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6ICV

Structure of SETD3 bound to SAH and unmodified actin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, B)
Histone-lysine N-methyltransferase setd3polymer50457824.72UniProt (Q86TU7)
Pfam (PF00856)
Pfam (PF09273)
Homo sapiens (Human)SET domain-containing protein 3
2B, D
(C, D)
Actin, cytoplasmic 1polymer232868.22UniProt (P60709)Homo sapiens (Human)Beta-actin
3E, F
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
4G, H, I, J
(A, C, B, D)
waterwater18.0591Chemie (HOH)
Sequence modifications
A, B: 1 - 503 (UniProt: Q86TU7)
PDBExternal DatabaseDetails
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight121385.9
Non-Polymers*Number of molecules2
Total formula weight768.8
All*Total formula weight122154.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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