6ICV
Structure of SETD3 bound to SAH and unmodified actin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SAH A 601 |
| Chain | Residue |
| A | ARG75 |
| A | ASN278 |
| A | HIS279 |
| A | TYR313 |
| A | SER325 |
| A | PHE327 |
| A | HOH757 |
| A | HOH789 |
| A | HOH842 |
| A | HOH853 |
| A | HOH881 |
| A | GLU103 |
| C | HIS73 |
| A | GLU104 |
| A | PHE106 |
| A | THR253 |
| A | ARG254 |
| A | ASP275 |
| A | MET276 |
| A | CYS277 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | binding site for residue SAH B 601 |
| Chain | Residue |
| B | ARG75 |
| B | GLU104 |
| B | PHE106 |
| B | THR253 |
| B | ARG254 |
| B | ASP275 |
| B | MET276 |
| B | CYS277 |
| B | ASN278 |
| B | HIS279 |
| B | TYR313 |
| B | SER325 |
| B | PHE327 |
| B | HOH785 |
| B | HOH800 |
| B | HOH830 |
| B | HOH837 |
| B | HOH839 |
| B | HOH850 |
| B | HOH872 |
| D | HIS73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:30526847, ECO:0000269|PubMed:30626964, ECO:0000269|PubMed:30785395, ECO:0000269|PubMed:31388018, ECO:0000269|PubMed:32503840 |
| Chain | Residue | Details |
| C | HIS73 | |
| B | SER325 | |
| D | HIS73 | |
| A | ARG254 | |
| A | ASP275 | |
| A | SER325 | |
| B | ARG75 | |
| B | GLU104 | |
| B | ARG254 | |
| B | ASP275 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-methyllysine => ECO:0000269|PubMed:23673617 |
| Chain | Residue | Details |
| C | LYS84 | |
| D | LYS84 |
