6IAN
T. brucei IFT22/74/81 GTP-bound crystal structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, B) | Intraflagellar transport protein 74 | polymer | 328 | 37731.6 | 2 | UniProt (Q57WF2) | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | |
| 2 | B, D (C, D) | Intraflagellar transport protein 81 | polymer | 454 | 52904.8 | 2 | UniProt (Q38BY1) Pfam (PF18383) | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) | |
| 3 | E (E) | Rab-like 5 | polymer | 220 | 24736.3 | 1 | UniProt (A0A3L6KZ98) Pfam (PF08477) UniProt (by SIFTS) (Q381A3) | Trypanosoma brucei equiperdum | |
| 4 | F (E) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 5 | G (E) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | H, I, J, K, L (A, C, B, D, E) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B: 79 - 401 (UniProt: Q57WF2)
C, D: 2 - 450 (UniProt: Q38BY1)
E: 2 - 220 (UniProt: A0A3L6KZ98)
| PDB | External Database | Details |
|---|---|---|
| Gly 74 | - | expression tag |
| Ala 75 | - | expression tag |
| Ala 76 | - | expression tag |
| Ser 77 | - | expression tag |
| Mse 78 | - | expression tag |
| Ala 199 | Thr 193 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Mse 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Mse 1 | - | initiating methionine |
| Pro 161 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 206009.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 547.5 | |
| All* | Total formula weight | 206556.6 |
