6I3Y

Crystal structure of the human mitochondrial PRELID1K58V-TRIAP1 complex with PS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (C, F)	PRELI domain-containing protein 1, mitochondrial	polymer	185	21551.3	2	UniProt (Q9Y255) Pfam (PF04707)	Homo sapiens (Human)	25 kDa protein of relevant evolutionary and lymphoid interest,Px19-like protein
2	C, D (A, H)	TP53-regulated inhibitor of apoptosis 1	polymer	90	10518.7	2	UniProt (O43715) Pfam (PF05254)	Homo sapiens (Human)	Protein 15E1.1,WF-1,p53-inducible cell-survival factor,p53CSV
3	E (C)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	1	Chemie (LMT)
4	F, G (C, F)	O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine	non-polymer		792.1	2	Chemie (P5S)
5	H, I, J (C, F, A)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

C, F: 12 - 184 (UniProt: Q9Y255)

PDB	External Database	Details
Gly 0	-	expression tag
Ser 1	-	expression tag
Ser 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
Ser 9	-	expression tag
Asp 10	-	expression tag
Gln 11	-	expression tag
Val 69	Lys 58	engineered mutation
Ser 123	Cys 112	conflict
Ser 126	Cys 115	conflict

A, H: 14 - 89 (UniProt: O43715)

PDB	External Database	Details
Met 0	-	initiating methionine
Ala 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
Val 8	-	expression tag
Asp 9	-	expression tag
Asp 10	-	expression tag
Asp 11	-	expression tag
Asp 12	-	expression tag
Lys 13	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	64140.0
Non-Polymers*	Number of molecules	3
	Total formula weight	2094.8
All*	Total formula weight	66234.8

*Water molecules are not included.