6I0M

Structure of human IMP dehydrogenase, isoform 2, bound to GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Inosine-5'-monophosphate dehydrogenase 2	polymer	517	56157.1	2	UniProt (P12268) Pfam (PF00478) Pfam (PF00571) In PDB	Homo sapiens (Human)	IMPDH 2,IMPDH-II
2	A, B	GUANOSINE-5'-MONOPHOSPHATE	non-polymer		363.2	2	Chemie (5GP)
3	A, B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	6	Chemie (GDP)
4	A, B	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
5		water	water		18.0	74	Chemie (HOH)

Sequence modifications

A, B: 1 - 514 (UniProt: P12268)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	112314.3
Non-Polymers*	Number of molecules	18
	Total formula weight	4346.3
All*	Total formula weight	116660.6

*Water molecules are not included.