6HJX

X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) 7'C pore mutant (L238C) in complex with nanobody 72

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Cys-loop ligand-gated ion channel	polymer	306	35244.1	1	UniProt (P0C7B7)	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
2	B (B)	Cys-loop ligand-gated ion channel	polymer	309	35555.4	1	UniProt (P0C7B7)	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
3	C (C)	Cys-loop ligand-gated ion channel	polymer	312	35880.8	1	UniProt (P0C7B7)	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
4	D (D)	Cys-loop ligand-gated ion channel	polymer	310	35726.7	1	UniProt (P0C7B7)	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
5	E (E)	Cys-loop ligand-gated ion channel	polymer	307	35359.1	1	UniProt (P0C7B7)	Dickeya chrysanthemi (Pectobacterium chrysanthemi)	ELIC
6	F, G, H, I, J (F, G, H, I, J)	nanobody 72	polymer	124	13368.0	5		Lama glama
7	K, O, T, V (A, B, D, E)	HEXAETHYLENE GLYCOL	non-polymer		282.3	4	Chemie (P6G)
8	L (A)	PHOSPHATIDYLETHANOLAMINE	non-polymer		734.0	1	Chemie (PTY)
9	M, N, P, S, U (A, B, C, D, E)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	5	Chemie (LMT)
10	Q (C)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
11	R (C)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
12	AA, BA, CA, DA, EA... (E, F, G, H, I...)	water	water		18.0	308	Chemie (HOH)

Sequence modifications

A: 9 - 314 (UniProt: P0C7B7)

B: 8 - 314 (UniProt: P0C7B7)

C: 8 - 317 (UniProt: P0C7B7)

D: 9 - 318 (UniProt: P0C7B7)

E: 8 - 314 (UniProt: P0C7B7)

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.