6H8P

JMJD2A/ KDM4A COMPLEXED WITH NI(II), NOG AND Histone H1.4(18-32)K26me3 peptide (15-mer)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysine-specific demethylase 4A	polymer	381	44326.3	2	UniProt (O75164) Pfam (PF02375) Pfam (PF02373)	Homo sapiens (Human)	JmjC domain-containing histone demethylation protein 3A,Jumonji domain-containing protein 2A
2	C, D (C, D)	Histone H1.4	polymer	15	1589.0	2	UniProt (P10412)	Homo sapiens	Histone H1b,Histone H1s-4
3	E, L (A, B)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
4	F, M (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	G, N (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	H, O (A, B)	N-OXALYLGLYCINE	non-polymer		147.1	2	Chemie (OGA)
7	I, J, K, P (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
8	Q, R, S, T (A, B, C, D)	water	water		18.0	454	Chemie (HOH)

Sequence modifications

A, B: 1 - 359 (UniProt: O75164)

PDB	External Database	Details
Met -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	91830.5
Non-Polymers*	Number of molecules	12
	Total formula weight	981.7
All*	Total formula weight	92812.2

*Water molecules are not included.