6H41
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-5 receptor subunit alpha | polymer | 309 | 35192.6 | 1 | UniProt (Q01344) Pfam (PF09240) | Homo sapiens (Human) | IL-5RA,CDw125 |
| 2 | B (B) | VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU | polymer | 18 | 2197.4 | 1 | synthetic construct | ||
| 3 | C (A) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A: 7 - 315 (UniProt: Q01344)
| PDB | External Database | Details |
|---|---|---|
| Ala 66 | Cys 86 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37390.1 | |
| All* | Total formula weight | 37390.1 |
