6H2S
Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant, pyruvate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase | polymer | 293 | 33074.3 | 4 | UniProt (O54288) Pfam (PF00701) UniProt (by SIFTS) (Q97U28) | Sulfolobus solfataricus | |
| 2 | E, J, M, P (A, B, C, D) | PYRUVIC ACID | non-polymer | 88.1 | 4 | Chemie (PYR) | |||
| 3 | F, G, K, L, N... (A, B, C, D) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 4 | H, O (A, C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 5 | I (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 6 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 731 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 294 (UniProt: O54288)
| PDB | External Database | Details |
|---|---|---|
| Val 157 | Thr 157 | engineered mutation |
| Gln 181 | Asp 181 | engineered mutation |
| Leu 198 | Ala 198 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 132297.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1269.2 | |
| All* | Total formula weight | 133566.5 |
