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6H1E

Crystal structure of C21orf127-TRMT112 in complex with SAH and H4 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HemK methyltransferase family member 2polymer20822344.71UniProt (Q9Y5N5)
Pfam (PF05175)
Homo sapiens (Human)M.HsaHemK2P,N(6)-adenine-specific DNA methyltransferase 1
2B
(B)
Multifunctional methyltransferase subunit TRM112-like proteinpolymer12614272.41UniProt (Q9UI30)
Pfam (PF03966)
Homo sapiens (Human)tRNA methyltransferase 112 homolog
3C
(S)
Histone H4 peptidepolymer212113.51Homo sapiens
4D
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
5E, F
(A, B)
waterwater18.074Chemie (HOH)
Sequence modifications
A: 8 - 214 (UniProt: Q9Y5N5)
PDBExternal DatabaseDetails
Ser 7-expression tag
B: 3 - 126 (UniProt: Q9UI30)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Gly 2-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight38730.6
Non-Polymers*Number of molecules1
Total formula weight384.4
All*Total formula weight39115.0
*Water molecules are not included.

243911

PDB entries from 2025-10-29

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