6GZD
Crystal structure of Human CSNK1A1 with A86
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Casein kinase I isoform alpha | polymer | 374 | 43075.2 | 1 | UniProt (P48729) Pfam (PF00069) In PDB | Homo sapiens (Human) | CKI-alpha,CK1 |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | A | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 3 | Chemie (PGE) | |||
| 4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
| 6 | A | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 7 | A | [4-[[4-[5-(cyclopropylmethyl)-1-methyl-pyrazol-4-yl]-5-fluoranyl-pyrimidin-2-yl]amino]cyclohexyl]azanium | non-polymer | 345.4 | 1 | Chemie (LCI) | |||
| 8 | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 337 (UniProt: P48729)
| PDB | External Database | Details |
|---|---|---|
| Met -36 | - | initiating methionine |
| Gly -35 | - | expression tag |
| Ser -34 | - | expression tag |
| Ser -33 | - | expression tag |
| His -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| Ser -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Gly -24 | - | expression tag |
| Val -23 | - | expression tag |
| Asp -22 | - | expression tag |
| Leu -21 | - | expression tag |
| Trp -20 | - | expression tag |
| Ser -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Gln -16 | - | expression tag |
| Phe -15 | - | expression tag |
| Glu -14 | - | expression tag |
| Lys -13 | - | expression tag |
| Gly -12 | - | expression tag |
| Thr -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Asn -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Tyr -7 | - | expression tag |
| Phe -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gly -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Gly 20 | Val 20 | conflict |
| Thr 35 | Ile 35 | conflict |
| His 58 | Leu 58 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43075.2 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2149.5 | |
| All* | Total formula weight | 45224.6 |
