6GVN
Tubulin:TM-3 DARPin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tubulin alpha chain | polymer | 451 | 50204.4 | 1 | UniProt (D0VWZ0) | Ovis aries (Sheep) | |
| 2 | B (B) | Tubulin beta chain | polymer | 445 | 49999.9 | 1 | UniProt (D0VWY9) | Ovis aries (Sheep) | |
| 3 | C (F) | TM-3 DARPIN | polymer | 169 | 18048.4 | 1 | synthetic construct | ||
| 4 | D, G (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | |||
| 5 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | I (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 8 | J, K (B, F) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 9 | L, M, N (A, B, F) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 1 - 451 (UniProt: D0VWZ0)
B: 1 - 455 (UniProt: D0VWY9)
| PDB | External Database | Details |
|---|---|---|
| Ser 232 | Gly 232 | conflict |
| Ser 340 | Thr 340 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Cys 203 | Ser 201 | conflict |
| Ile 318 | Val 316 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 118252.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1570.5 | |
| All* | Total formula weight | 119823.2 |
