6GVN
Tubulin:TM-3 DARPin complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005874 | cellular_component | microtubule |
| A | 0005879 | cellular_component | axonemal microtubule |
| A | 0005929 | cellular_component | cilium |
| A | 0007010 | biological_process | cytoskeleton organization |
| A | 0007017 | biological_process | microtubule-based process |
| A | 0015630 | cellular_component | microtubule cytoskeleton |
| A | 0030317 | biological_process | flagellated sperm motility |
| A | 0036126 | cellular_component | sperm flagellum |
| A | 0036464 | cellular_component | cytoplasmic ribonucleoprotein granule |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0055037 | cellular_component | recycling endosome |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005874 | cellular_component | microtubule |
| B | 0007010 | biological_process | cytoskeleton organization |
| B | 0007017 | biological_process | microtubule-based process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue GTP A 501 |
| Chain | Residue |
| A | GLY10 |
| A | GLY143 |
| A | GLY144 |
| A | THR145 |
| A | GLY146 |
| A | ILE171 |
| A | VAL177 |
| A | THR179 |
| A | GLU183 |
| A | ASN206 |
| A | TYR224 |
| A | GLN11 |
| A | ASN228 |
| A | ILE231 |
| A | MG502 |
| A | HOH602 |
| A | HOH603 |
| A | HOH605 |
| A | HOH612 |
| A | HOH621 |
| A | HOH627 |
| B | LYS254 |
| A | ALA12 |
| A | GLN15 |
| A | ASP69 |
| A | ASP98 |
| A | ALA99 |
| A | ASN101 |
| A | SER140 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 502 |
| Chain | Residue |
| A | GTP501 |
| A | HOH602 |
| A | HOH603 |
| A | HOH627 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | TYR262 |
| A | PRO263 |
| A | ARG264 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | binding site for residue GTP B 501 |
| Chain | Residue |
| B | GLY10 |
| B | GLN11 |
| B | CYS12 |
| B | GLN15 |
| B | ALA99 |
| B | GLY100 |
| B | ASN101 |
| B | SER140 |
| B | GLY143 |
| B | GLY144 |
| B | THR145 |
| B | GLY146 |
| B | VAL177 |
| B | SER178 |
| B | GLU183 |
| B | ASN206 |
| B | TYR224 |
| B | ASN228 |
| B | MG502 |
| B | HOH608 |
| B | HOH614 |
| B | HOH618 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MG B 502 |
| Chain | Residue |
| B | GLN11 |
| B | GTP501 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue MES B 503 |
| Chain | Residue |
| A | TRP407 |
| B | ARG158 |
| B | PRO162 |
| B | ASP163 |
| B | ARG164 |
| B | ASN197 |
| B | ASP199 |
| B | ARG253 |
| B | HOH625 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | THR180 |
| B | VAL182 |
| B | PHE404 |
| B | TRP407 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL F 201 |
| Chain | Residue |
| B | ASP179 |
| F | GLY91 |
| F | GLU127 |
Functional Information from PROSITE/UniProt
