6GU7
CDK1/Cks2 in complex with AZD5438
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | Cyclin-dependent kinase 1 | polymer | 302 | 34553.9 | 4 | UniProt (P06493) Pfam (PF00069) | Homo sapiens (Human) | CDK1,Cell division control protein 2 homolog,Cell division protein kinase 1,p34 protein kinase |
| 2 | B, D, F, H (B, D, F, H) | Cyclin-dependent kinases regulatory subunit 2 | polymer | 84 | 10290.8 | 4 | UniProt (P33552) Pfam (PF01111) | Homo sapiens (Human) | CKS-2 |
| 3 | I (A) | 4-(2-methyl-3-propan-2-yl-imidazol-4-yl)-~{N}-(4-methylsulfonylphenyl)pyrimidin-2-amine | non-polymer | 371.5 | 1 | Chemie (FB8) | |||
| 4 | J, K, L, M, N... (A, C, D, E, F...) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 297 (UniProt: P06493)
B, D, F, H: 1 - 79 (UniProt: P33552)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Leu -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 179378.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 371.5 | |
| All* | Total formula weight | 179750.3 |
