6GT6
Crystal structure of recombinant coagulation factor beta-XIIa
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | Coagulation factor XII | polymer | 253 | 27372.7 | 1 | UniProt (P00748) Pfam (PF00089) | Homo sapiens (Human) | Hageman factor,HAF |
| 2 | B (A) | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G62182OO) | |||
| 3 | C (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (B) | CYSTEINE | non-polymer | 121.2 | 1 | Chemie (CYS) | |||
| 6 | F (B) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
B: 16 - 244 (UniProt: P00748)
| PDB | External Database | Details |
|---|---|---|
| Thr 245 | - | expression tag |
| Arg 246 | - | expression tag |
| Thr 247 | - | expression tag |
| Gly 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| His 254 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27372.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 309.3 | |
| All* | Total formula weight | 28268.6 |
