6GT6

Crystal structure of recombinant coagulation factor beta-XIIa

Summary for 6GT6

Entry DOI	10.2210/pdb6gt6/pdb
Descriptor	Coagulation factor XII, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (6 entities in total)
Functional Keywords	human coagulation factor xiia, hydrolase, serine protease, blood clotting
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	28268.59
Authors	Pathak, M.,Emsley, J. (deposition date: 2018-06-15, release date: 2019-07-17, Last modification date: 2024-01-17)
Primary citation	Pathak, M.,Manna, R.,Li, C.,Kaira, B.G.,Hamad, B.K.,Belviso, B.D.,Bonturi, C.R.,Dreveny, I.,Fischer, P.M.,Dekker, L.V.,Oliva, M.L.V.,Emsley, J. Crystal structures of the recombinant beta-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics. Acta Crystallogr D Struct Biol, 75:578-591, 2019 Cited by PubMed: 31205020 DOI: 10.1107/S2059798319006910 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.54 Å)

Structure validation