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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

6GSN

Structure of a partial yeast 48S preinitiation complex in closed conformation

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1218S rRNA (1798-MER)polymer1798579239.61GenBank (49642208)Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
2CKLLA0F09812ppolymer21723162.91UniProt (Q6CKL3)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
3DKLLA0D08305ppolymer22324830.91UniProt (Q6CRK7)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
4FKLLA0D10659ppolymer20622912.41UniProt (Q6CRA3)
Pfam (PF00177)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
5KKLLA0B08173ppolymer9611423.11UniProt (Q6CVZ5)
Pfam (PF03501)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
6M40S ribosomal protein S12polymer11812710.51UniProt (Q6CLU4)
Pfam (PF01248)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
7PKLLA0F07843ppolymer11713220.61UniProt (Q6CKV4)
Pfam (PF00203)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
8Q40S ribosomal protein S16polymer14115656.31UniProt (Q875N2)
Pfam (PF00380)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
9RKLLA0B01474ppolymer13014886.21UniProt (Q6CWU3)
Pfam (PF00833)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
10SKLLA0B01562ppolymer14516953.41UniProt (Q6CWT9)
Pfam (PF00416)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
11TKLLA0A07194ppolymer14315747.81UniProt (Q6CXM0)
Pfam (PF01090)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
12UKLLA0F25542ppolymer10612032.11UniProt (Q6CIM1)
Pfam (PF00338)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
13ZKLLA0B06182ppolymer707939.21UniProt (Q6CW78)
Pfam (PF03297)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
14c40S ribosomal protein S28polymer626972.21UniProt (P33285)
Pfam (PF01200)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)S33
15fUbiquitin-40S ribosomal protein S27apolymer697958.41UniProt (P69061)
Pfam (PF01599)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
16gKLLA0E12277ppolymer32435612.71UniProt (Q6CNI7)
Pfam (PF00400)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
17d40S ribosomal protein S29polymer536322.11UniProt (Q6CPG3)
Pfam (PF00253)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
18e40S ribosomal protein S30polymer586608.81UniProt (Q6CUH5)
Pfam (PF04758)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
19h60S ribosomal protein L41-Apolymer253354.21UniProt (P0CX86)
Pfam (PF05162)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)L47,Large ribosomal subunit protein eL41-A,YL41
203mRNApolymer144321.61Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
21iEukaryotic translation initiation factor 1Apolymer11112659.41UniProt (P38912)
Pfam (PF01176)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF-1A,Eukaryotic translation initiation factor 4C,eIF-4C
22mEukaryotic translation initiation factor eIF-1polymer9010299.01UniProt (P32911)
Pfam (PF01253)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Protein translation factor SUI1
23oEukaryotic translation initiation factor 3 subunit A,eIF3apolymer56762822.81UniProt (P38249)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF3a,Eukaryotic translation initiation factor 3 110 kDa subunit homolog,eIF3 p110,Translation initiation factor eIF3,p110 subunit homolog
24qEukaryotic translation initiation factor 3 subunit Cpolymer69980545.91UniProt (P32497)
Pfam (PF05470)
Pfam (PF01399)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF3c,Eukaryotic translation initiation factor 3 93 kDa subunit,eIF3 p93,Nuclear transport protein NIP1,Translation initiation factor eIF3,p93 subunit
25kEukaryotic translation initiation factor 2 subunit gammapolymer43047230.11UniProt (P32481)
Pfam (PF00009)
Pfam (PF03144)
Pfam (PF09173)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF-2-gamma
26lEukaryotic translation initiation factor 2 subunit betapolymer14416458.11UniProt (P09064)
Pfam (PF01873)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF-2-beta
27jEukaryotic translation initiation factor 2 subunit alphapolymer26330222.01UniProt (P20459)
Pfam (PF00575)
Pfam (PF07541)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF-2-alpha
281tRNAi (75-MER)polymer7524223.51GenBank (176433)Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
29A40S ribosomal protein S0polymer21924368.71UniProt (Q6CN12)
Pfam (PF00318)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
30B40S ribosomal protein S1polymer23126404.71UniProt (Q6CWD0)
Pfam (PF01015)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
31E40S ribosomal protein S4polymer26029486.31UniProt (Q6CWJ2)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
Pfam (PF08071)
Pfam (PF01479)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
32G40S ribosomal protein S6polymer22625811.01UniProt (Q6CM04)
Pfam (PF01092)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
33H40S ribosomal protein S7polymer18421033.61UniProt (Q6CTD6)
Pfam (PF01251)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
34I40S ribosomal protein S8polymer20022511.51UniProt (Q6CMG3)
Pfam (PF01201)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
35JKLLA0E23673ppolymer18220882.31UniProt (Q6CM18)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
36LKLLA0A10483ppolymer15517712.71UniProt (Q6CX80)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
37NKLLA0F18040ppolymer15016858.71UniProt (Q6CJK0)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
38O40S ribosomal protein S14polymer12713458.41UniProt (P27069)
Pfam (PF00411)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)RP59
39V40S ribosomal protein S21polymer879797.91UniProt (Q6CXT6)
Pfam (PF01249)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
40W40S ribosomal protein S22polymer12914513.81UniProt (Q6CW21)
Pfam (PF00410)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
41Y40S ribosomal protein S24polymer13415063.41UniProt (Q6CU44)
Pfam (PF01282)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
42XRPS23polymer14415916.71UniProt (Q875M3)
Pfam (PF00164)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
43a40S ribosomal protein S26polymer9811166.21UniProt (Q6CS01)
Pfam (PF01283)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
44b40S ribosomal protein S27polymer818753.21UniProt (Q6CNL2)
Pfam (PF01667)
In PDB		Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast)
45pEukaryotic translation initiation factor 3 subunit Bpolymer66676738.91UniProt (P06103)
Pfam (PF00076)
Pfam (PF08662)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF3b,Cell cycle regulation and translation initiation protein,Eukaryotic translation initiation factor 3 90 kDa subunit,eIF3 p90,Translation initiation factor eIF3 p90 subunit
46sEukaryotic translation initiation factor 3 subunit Ipolymer34238229.81UniProt (A6ZMK5)
Pfam (PF00400)
UniProt (by SIFTS) (P40217)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF3i,Eukaryotic translation initiation factor 3 39 kDa subunit homolog,eIF-3 39 kDa subunit homolog
47rEukaryotic translation initiation factor 3 subunit Gpolymer495576.21UniProt (A6ZZ25)
Pfam (PF12353)
In PDB		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)eIF3g,Eukaryotic translation initiation factor 3 RNA-binding subunit,eIF-3 RNA-binding subunit,Translation initiation factor eIF3 p33 subunit homolog,eIF3 p33 homolog
482, B, a, C, h...MAGNESIUM IONnon-polymer24.381Chemie (MG)
49a, b, f, lZINC IONnon-polymer65.44Chemie (ZN)
50kPHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTERnon-polymer521.21Chemie (GCP)
51kMETHIONINEnon-polymer149.21Chemie (MET)
Sequence modifications
m: 19 - 108 (UniProt: P32911)
PDBExternal DatabaseDetails
Ala 20Thr 20conflict
Ala 23Ser 23conflict
o: 5 - 492 (UniProt: P38249)
o: 693 - 771 (PDB: 6GSN)
1: 1 - 76 (GenBank: 176433)
PDBExternal DatabaseDetails
U 31G 30conflict
A 39C 38conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains47
Total formula weight1540609.7
Non-Polymers*Number of molecules87
Total formula weight2900.8
All*Total formula weight1543510.5
*Water molecules are not included.

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PDB entries from 2024-04-17

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