6GO7
TdT chimera (Loop1 of pol mu) - full DNA synapsis complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase | polymer | 401 | 45849.0 | 1 | UniProt (P09838) UniProt (Q9JIW4) Pfam (PF14716) Pfam (PF10391) Pfam (PF01909) Pfam (PF14791) | Mus musculus (Mouse) | Terminal addition enzyme,Terminal deoxynucleotidyltransferase,Terminal transferase,Pol Mu,Terminal transferase,Terminal addition enzyme,Terminal deoxynucleotidyltransferase,Terminal transferase |
| 2 | B, E (F, G) | DNA (5'-D(*AP*AP*AP*AP*AP*C)-3') | polymer | 6 | 1810.3 | 2 | synthetic construct | ||
| 3 | C, D, F, G (E, H, I, J) | DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3') | polymer | 7 | 2094.4 | 4 | synthetic construct | ||
| 4 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | I (A) | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE | non-polymer | 451.2 | 1 | Chemie (DCT) | |||
| 6 | J (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | K, L, M, N, O... (A, F, E, H, I...) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A: 132 - 377 (UniProt: P09838)
A: 378 - 407 (UniProt: Q9JIW4)
A: 408 - 511 (UniProt: P09838)
| PDB | External Database | Details |
|---|---|---|
| Met 111 | - | initiating methionine |
| Gly 112 | - | expression tag |
| Ser 113 | - | expression tag |
| Ser 114 | - | expression tag |
| His 115 | - | expression tag |
| His 116 | - | expression tag |
| His 117 | - | expression tag |
| His 118 | - | expression tag |
| His 119 | - | expression tag |
| His 120 | - | expression tag |
| Ser 121 | - | expression tag |
| Ser 122 | - | expression tag |
| Gly 123 | - | expression tag |
| Leu 124 | - | expression tag |
| Val 125 | - | expression tag |
| Pro 126 | - | expression tag |
| Arg 127 | - | expression tag |
| Gly 128 | - | expression tag |
| Ser 129 | - | expression tag |
| His 130 | - | expression tag |
| Met 131 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Val 401 | Ala 386 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 57847.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 498.5 | |
| All* | Total formula weight | 58345.5 |
