6GO7

TdT chimera (Loop1 of pol mu) - full DNA synapsis complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006281	biological_process	DNA repair
A	0016779	molecular_function	nucleotidyltransferase activity
A	0034061	molecular_function	DNA polymerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue NA A 601

Chain	Residue
A	THR253
A	VAL255
A	VAL258
E	DG6

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site_id	AC2
Number of Residues	21
Details	binding site for residue DCT A 602

Chain	Residue
A	HIS342
A	ASP343
A	ASP345
A	TRP451
A	GLY453
A	ARG455
A	GLU458
A	MG603
A	HOH704
A	HOH705
A	HOH719
A	HOH742
A	HOH760
A	HOH762
E	DC7
H	DG6
A	GLY332
A	GLY333
A	ARG336
A	LYS338
A	GLY341

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site_id	AC3
Number of Residues	4
Details	binding site for residue MG A 603

Chain	Residue
A	ASP343
A	ASP345
A	DCT602
A	HOH752

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Functional Information from PROSITE/UniProt

site_id	PS00522
Number of Residues	20
Details	DNA_POLYMERASE_X DNA polymerase family X signature. GGFrRGkmtGhDVDFLItsP

Chain	Residue	Details
A	GLY332-PRO351

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305, ECO:0007744|PDB:4I2B, ECO:0007744|PDB:4I2C, ECO:0007744|PDB:4I2D, ECO:0007744|PDB:4I2E

Chain	Residue	Details
A	GLY333
A	HIS342
A	GLY450

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305, ECO:0007744|PDB:1JMS, ECO:0007744|PDB:4I2B

Chain	Residue	Details
A	ASP343
A	ASP345
A	ASP435

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
A	SER134

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 632

Chain	Residue	Details
A	ASP343	metal ligand
A	ASP345	metal ligand
A	ASP435	metal ligand, proton acceptor, proton donor

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