6GN0

Exoenzyme S from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	14-3-3 protein beta/alpha	polymer	248	28566.0	4	UniProt (P31946) Pfam (PF00244) In PDB	Homo sapiens (Human)	Protein 1054,Protein kinase C inhibitor protein 1,KCIP-1
2	E, F, G, H	Exoenzyme S	polymer	244	26213.0	4	UniProt (Q51451) Pfam (PF03496) UniProt (by SIFTS) (Q93SQ1) In PDB	Pseudomonas aeruginosa

Sequence modifications

A, B, C, D: 1 - 239 (UniProt: P31946)

PDB	External Database	Details
Glu 240	-	expression tag
Asn 241	-	expression tag
Leu 242	-	expression tag
Tyr 243	-	expression tag
Phe 244	-	expression tag
Gln 245	-	expression tag
Ser 246	-	expression tag
Leu 247	-	expression tag
Glu 248	-	expression tag

E, F, G, H: 234 - 453 (UniProt: Q51451)

PDB	External Database	Details
Met 210	-	initiating methionine
Gly 211	-	expression tag
Ser 212	-	expression tag
Ser 213	-	expression tag
His 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
Ser 220	-	expression tag
Gln 221	-	expression tag
Asp 222	-	expression tag
Pro 223	-	expression tag
Asn 224	-	expression tag
Ser 225	-	expression tag
Glu 226	-	expression tag
Asn 227	-	expression tag
Leu 228	-	expression tag
Tyr 229	-	expression tag
Phe 230	-	expression tag
Gln 231	-	expression tag
Gly 232	-	expression tag
Ala 233	-	expression tag
Ala 379	Glu 379	engineered mutation
Ala 381	Glu 381	engineered mutation
Leu 415	Gln 415	conflict
Pro 434	Arg 434	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	219115.8
All*	Total formula weight	219115.8

*Water molecules are not included.