6GMR
pVHL:EloB:EloC in complex with (4-(1H-pyrrol-1-yl)phenyl)methanol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Elongin-B | polymer | 118 | 13147.8 | 1 | UniProt (Q15370) Pfam (PF00240) In PDB | Homo sapiens (Human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
2 | C | Elongin-C | polymer | 97 | 10974.6 | 1 | UniProt (Q15369) Pfam (PF03931) In PDB | Homo sapiens (Human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
3 | H | Hypoxia inducible factor 1alpha, residues 559-577 | polymer | 19 | 2260.5 | 1 | Pfam (PF11413) UniProt (by SIFTS) (Q16665) In PDB | Homo sapiens | |
4 | V | von Hippel-Lindau disease tumor suppressor | polymer | 163 | 18840.4 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) In PDB | Homo sapiens (Human) | Protein G7,pVHL |
5 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
6 | V | (4-pyrrol-1-ylphenyl)methanol | non-polymer | 173.2 | 1 | Chemie (F4K) | |||
7 | V | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
8 | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
C: 17 - 112 (UniProt: Q15369)
V: 54 - 213 (UniProt: P40337)
PDB | External Database | Details |
---|---|---|
Met 16 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Gly 51 | - | expression tag |
Ser 52 | - | expression tag |
His 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 45223.3 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 361.4 | |
All* | Total formula weight | 45584.7 |