6GMN
pVHL:EloB:EloC in complex with methyl 4H-furo[3,2-b]pyrrole-5-carboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Elongin-B | polymer | 104 | 11852.4 | 1 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (Human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 2 | B, E, H, K (B, E, H, K) | Elongin-C | polymer | 97 | 10974.6 | 4 | UniProt (Q15369) Pfam (PF03931) | Homo sapiens (Human) | EloC,Elongin 15 kDa subunit,RNA polymerase II transcription factor SIII subunit C,SIII p15,Transcription elongation factor B polypeptide 1 |
| 3 | C, F, L (C, F, L) | von Hippel-Lindau disease tumor suppressor | polymer | 162 | 18806.3 | 3 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (Human) | Protein G7,pVHL |
| 4 | D, G, J (D, G, J) | Elongin-B | polymer | 104 | 11956.4 | 3 | UniProt (Q15370) Pfam (PF00240) | Homo sapiens (Human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 5 | I (I) | von Hippel-Lindau disease tumor suppressor | polymer | 162 | 18702.3 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) | Homo sapiens (Human) | Protein G7,pVHL |
| 6 | M, O, P, Q, S (A, C, F, I, L) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 7 | N, R (B, K) | methyl 4~{H}-furo[3,2-b]pyrrole-5-carboxylate | non-polymer | 165.1 | 2 | Chemie (F4E) | |||
| 8 | AA, BA, CA, DA, EA... (H, I, J, K, L...) | water | water | 18.0 | 839 | Chemie (HOH) |
Sequence modifications
B, E, H, K: 17 - 112 (UniProt: Q15369)
C, F, L: 54 - 213 (UniProt: P40337)
I: 54 - 213 (UniProt: P40337)
| PDB | External Database | Details |
|---|---|---|
| Met 16 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 52 | - | expression tag |
| Ser 53 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 166741.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 625.5 | |
| All* | Total formula weight | 167366.6 |
