6GMN
pVHL:EloB:EloC in complex with methyl 4H-furo[3,2-b]pyrrole-5-carboxylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| A | 0030891 | cellular_component | VCB complex |
| A | 0070449 | cellular_component | elongin complex |
| B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| D | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| D | 0030891 | cellular_component | VCB complex |
| D | 0070449 | cellular_component | elongin complex |
| E | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| G | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| G | 0030891 | cellular_component | VCB complex |
| G | 0070449 | cellular_component | elongin complex |
| H | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| J | 0006368 | biological_process | transcription elongation by RNA polymerase II |
| J | 0030891 | cellular_component | VCB complex |
| J | 0070449 | cellular_component | elongin complex |
| K | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | HIS10 |
| A | LYS11 |
| A | THR12 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue F4E B 201 |
| Chain | Residue |
| L | GLY106 |
| B | GLU64 |
| B | ILE65 |
| B | PRO66 |
| B | GLU102 |
| B | MET105 |
| B | PHE109 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue ACT C 301 |
| Chain | Residue |
| C | ARG161 |
| C | HOH423 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue ACT F 301 |
| Chain | Residue |
| F | ARG82 |
| F | ARG161 |
| F | HOH426 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue ACT I 301 |
| Chain | Residue |
| I | ARG161 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue F4E K 201 |
| Chain | Residue |
| K | GLU64 |
| K | ILE65 |
| K | PRO66 |
| K | GLU102 |
| K | MET105 |
| K | ALA106 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue ACT L 301 |
| Chain | Residue |
| L | ARG161 |
| L | HOH412 |
| L | HOH470 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | MOD_RES: N-acetylmethionine => ECO:0000269|Ref.6, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| D | MET1 | |
| G | MET1 | |
| J | MET1 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P62869 |
| Chain | Residue | Details |
| D | THR84 | |
| G | THR84 | |
| J | THR84 |
