6GLW
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Galectin-10 | polymer | 179 | 20628.2 | 2 | UniProt (Q05315) Pfam (PF00337) | Homo sapiens (Human) | Gal-10,Charcot-Leyden crystal protein,CLC,Eosinophil lysophospholipase,Lysolecithin acylhydrolase |
| 2 | C, E (C, H) | Fab 1D11 - Heavy chain | polymer | 230 | 24601.5 | 2 | Lama glama (llama) | ||
| 3 | D, F (D, L) | Fab 1D11 - Light chain | polymer | 216 | 22817.1 | 2 | Lama glama (llama) | ||
| 4 | G (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | H (H) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | I, J, K, L, M... (A, B, C, D, H...) | water | water | 18.0 | 1535 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 142 (UniProt: Q05315)
| PDB | External Database | Details |
|---|---|---|
| Met -36 | - | initiating methionine |
| Ala -35 | - | expression tag |
| Ser -34 | - | expression tag |
| Thr -33 | - | expression tag |
| Thr -32 | - | expression tag |
| His -31 | - | expression tag |
| His -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| Asp -25 | - | expression tag |
| Thr -24 | - | expression tag |
| Asp -23 | - | expression tag |
| Ile -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Thr -20 | - | expression tag |
| Thr -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Arg -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Asp -10 | - | expression tag |
| Asp -9 | - | expression tag |
| Lys -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 136093.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 253.3 | |
| All* | Total formula weight | 136346.7 |
