6GLW

Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Galectin-10	polymer	179	20628.2	2	UniProt (Q05315) Pfam (PF00337) In PDB	Homo sapiens (Human)	Gal-10,Charcot-Leyden crystal protein,CLC,Eosinophil lysophospholipase,Lysolecithin acylhydrolase
2	C, H	Fab 1D11 - Heavy chain	polymer	230	24601.5	2		Lama glama (llama)
3	D, L	Fab 1D11 - Light chain	polymer	216	22817.1	2		Lama glama (llama)
4	B	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
5	H	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
6		water	water		18.0	1535	Chemie (HOH)

Sequence modifications

A, B: 1 - 142 (UniProt: Q05315)

PDB	External Database	Details
Met -36	-	initiating methionine
Ala -35	-	expression tag
Ser -34	-	expression tag
Thr -33	-	expression tag
Thr -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
Asp -25	-	expression tag
Thr -24	-	expression tag
Asp -23	-	expression tag
Ile -22	-	expression tag
Pro -21	-	expression tag
Thr -20	-	expression tag
Thr -19	-	expression tag
Gly -18	-	expression tag
Gly -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
Arg -14	-	expression tag
Pro -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Asp -10	-	expression tag
Asp -9	-	expression tag
Lys -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	136093.5
Non-Polymers*	Number of molecules	2
	Total formula weight	253.3
All*	Total formula weight	136346.7

*Water molecules are not included.