6GLW
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 1D11
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002667 | biological_process | regulation of T cell anergy |
| A | 0002724 | biological_process | regulation of T cell cytokine production |
| A | 0004622 | molecular_function | phosphatidylcholine lysophospholipase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0031012 | cellular_component | extracellular matrix |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046006 | biological_process | regulation of activated T cell proliferation |
| A | 0070231 | biological_process | T cell apoptotic process |
| B | 0002667 | biological_process | regulation of T cell anergy |
| B | 0002724 | biological_process | regulation of T cell cytokine production |
| B | 0004622 | molecular_function | phosphatidylcholine lysophospholipase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0031012 | cellular_component | extracellular matrix |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046006 | biological_process | regulation of activated T cell proliferation |
| B | 0070231 | biological_process | T cell apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 B 201 |
| Chain | Residue |
| B | GLU90 |
| B | LYS134 |
| B | ASN136 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue ACT H 301 |
| Chain | Residue |
| H | HOH531 |
| A | TYR8 |
| A | HOH278 |
| H | ASN165 |
| H | THR203 |
| H | HOH460 |
| H | HOH498 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH |
| Chain | Residue | Details |
| C | TYR204-HIS210 | |
| D | TYR195-HIS201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 264 |
| Details | Domain: {"description":"Galectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00639","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Not glycosylated","evidences":[{"source":"PubMed","id":"16457599","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"16457599","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
