6GKU
Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Galectin-10 | polymer | 180 | 20685.2 | 1 | UniProt (Q05315) Pfam (PF00337) In PDB | Homo sapiens (Human) | Gal-10,Charcot-Leyden crystal protein,CLC,Eosinophil lysophospholipase,Lysolecithin acylhydrolase |
2 | H | Fab 6F5 - Heavy Chain | polymer | 228 | 24206.0 | 1 | Lama glama (llama) | ||
3 | L | Fab 6F5 - Light chain | polymer | 216 | 22872.3 | 1 | Lama glama (llama) | ||
4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | L | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
6 | water | water | 18.0 | 823 | Chemie (HOH) |
Sequence modifications
A: 1 - 142 (UniProt: Q05315)
PDB | External Database | Details |
---|---|---|
Met -37 | - | initiating methionine |
Ala -36 | - | expression tag |
Ser -35 | - | expression tag |
Thr -34 | - | expression tag |
Thr -33 | - | expression tag |
His -32 | - | expression tag |
His -31 | - | expression tag |
His -30 | - | expression tag |
His -29 | - | expression tag |
His -28 | - | expression tag |
His -27 | - | expression tag |
Asp -26 | - | expression tag |
Thr -25 | - | expression tag |
Asp -24 | - | expression tag |
Ile -23 | - | expression tag |
Pro -22 | - | expression tag |
Thr -21 | - | expression tag |
Thr -20 | - | expression tag |
Gly -19 | - | expression tag |
Gly -18 | - | expression tag |
Gly -17 | - | expression tag |
Ser -16 | - | expression tag |
Arg -15 | - | expression tag |
Pro -14 | - | expression tag |
Asp -13 | - | expression tag |
Asp -12 | - | expression tag |
Asp -11 | - | expression tag |
Asp -10 | - | expression tag |
Lys -9 | - | expression tag |
Glu -8 | - | expression tag |
Asn -7 | - | expression tag |
Leu -6 | - | expression tag |
Tyr -5 | - | expression tag |
Phe -4 | - | expression tag |
Gln -3 | - | expression tag |
Gly -2 | - | expression tag |
Gly -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 67763.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 190.3 | |
All* | Total formula weight | 67953.8 |