6GKU

Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 6F5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002667	biological_process	regulation of T cell anergy
A	0002724	biological_process	regulation of T cell cytokine production
A	0004622	molecular_function	phosphatidylcholine lysophospholipase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0030246	molecular_function	carbohydrate binding
A	0031012	cellular_component	extracellular matrix
A	0042802	molecular_function	identical protein binding
A	0046006	biological_process	regulation of activated T cell proliferation
A	0070231	biological_process	T cell apoptotic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue CA A 201

Chain	Residue
A	ASN80
A	GLN107
A	SER108
A	SER109
A	HOH448

---

site_id	AC2
Number of Residues	6
Details	binding site for residue PGE L 301

Chain	Residue
L	GLY104
L	HOH537
H	GLY42
L	PRO8
L	TYR89
L	GLY103

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR202-HIS208
L	TYR195-HIS201

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	132
Details	Domain: {"description":"Galectin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00639","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"Not glycosylated","evidences":[{"source":"PubMed","id":"16457599","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"16457599","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---