6GH9
USP15 catalytic domain in complex with small molecule
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ubiquitin carboxyl-terminal hydrolase 15 | polymer | 365 | 41747.2 | 2 | UniProt (Q9Y4E8) Pfam (PF00443) In PDB | Homo sapiens (Human) | Deubiquitinating enzyme 15,Ubiquitin thioesterase 15,Ubiquitin-specific-processing protease 15,Unph-2,Unph4 |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | A | 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE | non-polymer | 444.5 | 1 | Chemie (MIX) | |||
5 | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A, B: 255 - 439 (UniProt: Q9Y4E8)
A, B: 757 - 922 (UniProt: Q9Y4E8)
PDB | External Database | Details |
---|---|---|
Met 254 | - | initiating methionine |
PDB | External Database | Details |
---|---|---|
Ala 440 | - | linker |
Ser 753 | - | linker |
Thr 754 | - | linker |
Ser 755 | - | linker |
Lys 756 | - | linker |
Ala 920 | Lys 920 | conflict |
Ala 921 | Gly 921 | conflict |
Leu 923 | - | expression tag |
Glu 924 | - | expression tag |
His 925 | - | expression tag |
His 926 | - | expression tag |
His 927 | - | expression tag |
His 928 | - | expression tag |
His 929 | - | expression tag |
His 930 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 83494.5 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 588.0 | |
All* | Total formula weight | 84082.5 |