6GCW
Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Focal adhesion kinase 1 | polymer | 276 | 31731.8 | 2 | UniProt (Q00944) Pfam (PF07714) | Gallus gallus (Chicken) | FADK 1,Focal adhesion kinase-related nonkinase,p41/p43FRNK,Protein-tyrosine kinase 2,p125FAK,pp125FAK |
| 2 | C, E (A, B) | 2-[[5-chloranyl-2-[[4-[[[1-[2-(propanoylamino)ethyl]-1,2,3-triazol-4-yl]methylamino]methyl]phenyl]amino]pyrimidin-4-yl]amino]-~{N}-methyl-benzamide | non-polymer | 563.1 | 2 | Chemie (EUQ) | |||
| 3 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63463.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1222.2 | |
| All* | Total formula weight | 64685.8 |
