6GCW

Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Focal adhesion kinase 1	polymer	276	31731.8	2	UniProt (Q00944) Pfam (PF07714) In PDB	Gallus gallus (Chicken)	FADK 1,Focal adhesion kinase-related nonkinase,p41/p43FRNK,Protein-tyrosine kinase 2,p125FAK,pp125FAK
2	A, B	2-[[5-chloranyl-2-[[4-[[[1-[2-(propanoylamino)ethyl]-1,2,3-triazol-4-yl]methylamino]methyl]phenyl]amino]pyrimidin-4-yl]amino]-~{N}-methyl-benzamide	non-polymer		563.1	2	Chemie (EUQ)
3	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4		water	water		18.0	300	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63463.6
Non-Polymers*	Number of molecules	3
	Total formula weight	1222.2
All*	Total formula weight	64685.8

*Water molecules are not included.