Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue EUQ A 701 |
| Chain | Residue |
| A | ILE428 |
| A | CYS502 |
| A | GLY505 |
| A | GLU506 |
| A | LEU553 |
| B | VAL513 |
| B | HOH870 |
| A | GLY429 |
| A | GLU430 |
| A | VAL436 |
| A | ALA452 |
| A | LYS454 |
| A | MET499 |
| A | GLU500 |
| A | LEU501 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 702 |
| Chain | Residue |
| A | SER601 |
| A | ARG668 |
| A | HOH856 |
| A | HOH876 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue EUQ B 701 |
| Chain | Residue |
| A | ASP630 |
| B | ILE428 |
| B | ALA452 |
| B | MET499 |
| B | GLU500 |
| B | LEU501 |
| B | CYS502 |
| B | GLY505 |
| B | LEU553 |
| B | GLY563 |
| B | ASP564 |
| B | LEU567 |
| B | SER568 |
| B | HOH839 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 27 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGQFGDVHqGiymspenpama.......VAIK |
| Chain | Residue | Details |
| A | ILE428-LYS454 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDIAARNVLV |
| Chain | Residue | Details |
| A | PHE542-VAL554 | |
| site_id | PS00661 |
| Number of Residues | 31 |
| Details | FERM_2 FERM domain signature 2. HrdiaarnvlVSatdCVklgDfgLsrYMeDS |
| Chain | Residue | Details |
| A | HIS544-SER574 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP546 | |
| B | ASP546 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE428 | |
| A | LYS454 | |
| A | GLU500 | |
| B | ILE428 | |
| B | LYS454 | |
| B | GLU500 | |
| Chain | Residue | Details |
| A | TYR576 | |
| B | TYR576 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by SRC => ECO:0000250 |
| Chain | Residue | Details |
| A | TYR577 | |
| B | TYR577 | |
