6G2N
Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PAU
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 5'(3')-deoxyribonucleotidase, cytosolic type | polymer | 205 | 23870.3 | 2 | UniProt (Q8TCD5) Pfam (PF06941) In PDB | Homo sapiens (Human) | Cytosolic 5',3'-pyrimidine nucleotidase,Deoxy-5'-nucleotidase 1,dNT-1 |
| 2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | A, B | [(2~{R},4~{a}~{R},6~{R},7~{a}~{R})-6-[2,4-bis(oxidanylidene)-5-[(~{E})-3-phosphonoprop-1-enyl]pyrimidin-1-yl]-2-phenyl-4~{a},6,7,7~{a}-tetrahydro-4~{H}-furo[3,2-d][1,3]dioxin-2-yl]phosphonic acid | non-polymer | 516.3 | 2 | Chemie (O84) | |||
| 4 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A, B: 6 - 205 (UniProt: Q8TCD5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
| Asn 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Ala 4 | - | expression tag |
| Ser 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47740.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1081.3 | |
| All* | Total formula weight | 48821.8 |
