6G05
RORGT (264-518;C455S) IN COMPLEX WITH INVERSE AGONIST "CPD-2" AND RIP140 PEPTIDE AT 1.90A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nuclear receptor ROR-gamma | polymer | 257 | 29739.3 | 2 | UniProt (P51449) Pfam (PF00104) In PDB | Homo sapiens (Human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
2 | P, Q | Nuclear receptor-interacting protein 1 | polymer | 20 | 2319.6 | 2 | UniProt (P48552) In PDB | Homo sapiens (Human) | Nuclear factor RIP140,Receptor-interacting protein 140 |
3 | A, B | 2-(4-ethylsulfonylphenyl)-~{N}-[4-phenyl-5-(phenylcarbonyl)-1,3-thiazol-2-yl]ethanamide | non-polymer | 490.6 | 2 | Chemie (EF5) | |||
4 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A, B: 263 - 518 (UniProt: P51449)
PDB | External Database | Details |
---|---|---|
Gly 262 | - | expression tag |
Ser 455 | Cys 455 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 64117.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 981.2 | |
All* | Total formula weight | 65099.0 |