6FYM
Human PARP14 (ARTD8), catalytic fragment in complex with inhibitor ITK1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Poly [ADP-ribose] polymerase 14 | polymer | 193 | 22118.6 | 4 | UniProt (Q460N5) Pfam (PF00644) In PDB | Homo sapiens (Human) | PARP-14,ADP-ribosyltransferase diphtheria toxin-like 8,ARTD8,B aggressive lymphoma protein 2 |
| 2 | A, B, C, D | 7,8-dimethyl-2-(pyrimidin-2-ylsulfanylmethyl)-3~{H}-quinazolin-4-one | non-polymer | 298.4 | 4 | Chemie (EBB) | |||
| 3 | C, D | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 4 | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1611 - 1801 (UniProt: Q460N5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1609 | - | expression tag |
| Met 1610 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 88474.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1317.5 | |
| All* | Total formula weight | 89791.8 |
