6FWX

Chimeric titin Z1Z2-Z1Z2 tandem (Z1212) functionalized with a GRGDS exogenous peptide from fibronectin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Titin,Titin,Titin	polymer	394	41934.5	2	UniProt (Q8WZ42) Pfam (PF07679) In PDB	Homo sapiens (Human)	Connectin,Rhabdomyosarcoma antigen MU-RMS-40.14,Connectin,Rhabdomyosarcoma antigen MU-RMS-40.14,Connectin,Rhabdomyosarcoma antigen MU-RMS-40.14
2	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)

Sequence modifications

A, B: 1 - 196 (UniProt: Q8WZ42)
A, B: 197 - 242 (UniProt: Q8WZ42)
A, B: 250 - 394 (UniProt: Q8WZ42)

PDB	External Database	Details
Ser 243	-	linker
Gly 244	-	linker
Arg 245	-	linker
Gly 246	-	linker
Asp 247	-	linker
Ser 248	-	linker
Ser 249	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	83869.0
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	83993.1

*Water molecules are not included.