6FUT
Complement factor D in complex with the inhibitor (S)-3'-(aminomethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-[1,1'-biphenyl]-3-carboxamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Complement factor D | polymer | 232 | 24739.1 | 1 | UniProt (P00746) Pfam (PF00089) In PDB | Homo sapiens (Human) | Adipsin,C3 convertase activator,Properdin factor D |
2 | A | 3-[3-(aminomethyl)phenyl]-~{N}-[(1~{S})-1,2,3,4-tetrahydronaphthalen-1-yl]benzamide | non-polymer | 356.5 | 1 | Chemie (E82) | |||
3 | A | SUCCINIC ACID | non-polymer | 118.1 | 1 | Chemie (SIN) | |||
4 | water | water | 18.0 | 318 | Chemie (HOH) |
Sequence modifications
A: 16 - 243 (UniProt: P00746)
PDB | External Database | Details |
---|---|---|
Ser 244 | - | expression tag |
Ala 245 | - | expression tag |
Ala 246 | - | expression tag |
Ala 247 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 24739.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 474.5 | |
All* | Total formula weight | 25213.7 |