Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0006508 | biological_process | proteolysis |
A | 0006956 | biological_process | complement activation |
A | 0006957 | biological_process | complement activation, alternative pathway |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0009617 | biological_process | response to bacterium |
A | 0031093 | cellular_component | platelet alpha granule lumen |
A | 0034774 | cellular_component | secretory granule lumen |
A | 0070062 | cellular_component | extracellular exosome |
A | 1904813 | cellular_component | ficolin-1-rich granule lumen |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 20 |
Details | binding site for residue E82 A 301 |
Chain | Residue |
A | HIS146 |
A | ARG218 |
A | VAL219 |
A | CYS220 |
A | SER240 |
A | SER244 |
A | SIN302 |
A | HOH410 |
A | HOH509 |
A | HOH517 |
A | HOH521 |
A | ASP189 |
A | HOH529 |
A | SER190 |
A | CYS191 |
A | LYS192 |
A | SER195 |
A | THR214 |
A | SER215 |
A | SER217 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue SIN A 302 |
Chain | Residue |
A | LEU41 |
A | HIS57 |
A | LYS192 |
A | GLY193 |
A | SER195 |
A | E82301 |
A | HOH403 |
A | HOH445 |
A | HOH461 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |