6FRK
Structure of a prehandover mammalian ribosomal SRP and SRP receptor targeting complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | Canis lupus familiaris RNA, 7SL, cytoplasmic 1 (RN7SL1), SRP RNA | polymer | 299 | 96826.3 | 1 | GenBank (577019609) | Canis lupus familiaris | |
| 2 | B (2) | tRNA | polymer | 76 | 24437.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 3 | C (3) | Ribosomal protein eL28 | polymer | 125 | 14301.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 4 | D (4) | Ribosomal protein L12 | polymer | 163 | 17689.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 5 | E (5) | 28S ribosomal RNA | polymer | 3658 | 1185357.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 6 | F (6) | 60S acidic ribosomal protein P0 | polymer | 202 | 22217.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 7 | G (7) | 5S ribosomal RNA | polymer | 120 | 38691.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 8 | H (8) | 5.8S ribosomal RNA | polymer | 156 | 50143.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 9 | I (A) | Ribosomal protein L8 | polymer | 244 | 26570.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 10 | J (B) | Ribosomal protein uL3 | polymer | 394 | 44759.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 11 | K (C) | Ribosomal protein uL4 | polymer | 367 | 41635.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 12 | L (D) | Ribosomal protein uL18 | polymer | 292 | 33942.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 13 | M (E) | Ribosomal protein eL6 | polymer | 236 | 27052.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 14 | N (F) | Ribosomal protein uL30 | polymer | 225 | 26590.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 15 | O (G) | Ribosomal protein eL8 | polymer | 238 | 27258.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 16 | P (H) | Ribosomal protein uL6 | polymer | 190 | 21655.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 17 | Q (I) | Ribosomal protein uL16 | polymer | 213 | 24465.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 18 | R (J) | Ribosomal protein uL5 | polymer | 170 | 19359.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 19 | S (L) | Ribosomal protein eL13 | polymer | 210 | 24234.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 20 | T (M) | Ribosomal protein eL14 | polymer | 138 | 16129.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 21 | U (N) | Ribosomal protein L15 | polymer | 203 | 24076.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 22 | V (O) | Ribosomal protein uL13 | polymer | 201 | 23435.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 23 | W (P) | Ribosomal protein uL22 | polymer | 153 | 17757.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 24 | X (Q) | Ribosomal protein eL18 | polymer | 187 | 21457.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 25 | Y (R) | Ribosomal protein eL19 | polymer | 180 | 21613.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 26 | Z (S) | Ribosomal protein eL20 | polymer | 175 | 20696.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 27 | AA (T) | Ribosomal protein eL21 | polymer | 159 | 18478.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 28 | BA (U) | Ribosomal protein eL22 | polymer | 99 | 11481.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 29 | CA (V) | Ribosomal protein L23 | polymer | 131 | 13972.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 30 | DA (W) | Ribosomal protein eL24 | polymer | 63 | 7512.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 31 | EA (X) | Ribosomal protein uL23 | polymer | 119 | 13856.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 32 | FA (Y) | Ribosomal protein uL24 | polymer | 134 | 15891.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 33 | GA (Z) | 60S ribosomal protein L27 | polymer | 135 | 15704.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 34 | HA (a) | Ribosomal protein uL15 | polymer | 147 | 16503.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 35 | IA (b) | 60S ribosomal protein L29 | polymer | 75 | 8722.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 36 | JA (c) | Ribosomal protein eL30 | polymer | 94 | 10496.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 37 | KA (d) | Ribosomal protein eL31 | polymer | 107 | 12635.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 38 | LA (e) | Ribosomal protein eL32 | polymer | 128 | 15022.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 39 | MA (f) | Ribosomal protein eL33 | polymer | 109 | 12433.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 40 | NA (g) | Ribosomal protein eL34 | polymer | 114 | 12994.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 41 | OA (h) | Ribosomal protein uL29 | polymer | 122 | 14460.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 42 | PA (i) | Ribosomal protein eL36 | polymer | 102 | 11915.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 43 | QA (j) | Ribosomal protein L37 | polymer | 86 | 10102.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 44 | RA (k) | Ribosomal protein eL38 | polymer | 69 | 8107.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 45 | SA (l) | Ribosomal protein eL39 | polymer | 50 | 6295.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 46 | TA (m) | Ribosomal protein eL40 | polymer | 52 | 6199.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 47 | UA (n) | Ribosomal protein eL41 | polymer | 23 | 3213.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 48 | VA (o) | Ribosomal protein eL42 | polymer | 104 | 12198.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 49 | WA (p) | Ribosomal protein eL43 | polymer | 91 | 10168.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 50 | XA (q) | Signal recognition particle subunit SRP19 | polymer | 105 | 12159.2 | 1 | UniProt (J9PAS6) Pfam (PF01922) | Canis lupus familiaris (Dog) | |
| 51 | YA (r) | Signal recognition particle subunit SRP72,Signal recognition particle subunit SRP72,Signal recognition particle subunit SRP72 | polymer | 605 | 67314.9 | 1 | UniProt (P33731) Pfam (PF17004) Pfam (PF13181) Pfam (PF08492) | Canis lupus familiaris (Dog) | SRP72,Signal recognition particle 72 kDa protein,SRP72,Signal recognition particle 72 kDa protein |
| 52 | ZA (t) | Signal sequence | polymer | 11 | 1262.8 | 1 | Saccharomyces cerevisiae (baker's yeast) | ||
| 53 | AB (u) | Signal recognition particle subunit SRP68 | polymer | 568 | 65570.0 | 1 | UniProt (Q00004) Pfam (PF16969) | Canis lupus familiaris (Dog) | SRP68,Signal recognition particle 68 kDa protein |
| 54 | BB (v) | SRP receptor beta subunit | polymer | 213 | 23588.0 | 1 | UniProt (G1STG2) Pfam (PF09439) | Oryctolagus cuniculus (Rabbit) | |
| 55 | CB (w) | Signal recognition particle 9 kDa protein | polymer | 74 | 8694.1 | 1 | UniProt (P21262) Pfam (PF05486) | Canis lupus familiaris (Dog) | SRP9 |
| 56 | DB (x) | Signal recognition particle 54 kDa protein | polymer | 504 | 55775.7 | 1 | UniProt (P61010) Pfam (PF02978) Pfam (PF02881) Pfam (PF00448) | Canis lupus familiaris (Dog) | SRP54 |
| 57 | EB (y) | SRP receptor alpha subunit | polymer | 657 | 72232.6 | 1 | UniProt (G1TCX6) Pfam (PF04086) Pfam (PF02881) Pfam (PF00448) | Oryctolagus cuniculus (Rabbit) | |
| 58 | FB (z) | Signal recognition particle 14 kDa protein | polymer | 110 | 12512.7 | 1 | UniProt (P16255) Pfam (PF02290) | Canis lupus familiaris (Dog) | SRP14 |
| 59 | AC, AD, AE, AF, AG... (5, 8, P, V, v...) | MAGNESIUM ION | non-polymer | 24.3 | 133 | Chemie (MG) PubChem (888) | |||
| 60 | GG, HG, IG (j, m, o) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 61 | KG (v) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) | |||
| 62 | LG, NG (x, y) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) |
Sequence modifications
r: 1 - 581 (UniProt: P33731)
r: 582 - 605 (PDB: 6FRK)
v: 60 - 271 (UniProt: G1STG2)
y: 1 - 637 (UniProt: G1TCX6)
r: 582 - 605 (PDB: 6FRK)
v: 60 - 271 (UniProt: G1STG2)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 58 |
| Total formula weight | 2499831.3 | |
| Non-Polymers* | Number of molecules | 139 |
| Total formula weight | 4996.4 | |
| All* | Total formula weight | 2504827.7 |
