6FRK
Structure of a prehandover mammalian ribosomal SRP and SRP receptor targeting complex
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | Canis lupus familiaris RNA, 7SL, cytoplasmic 1 (RN7SL1), SRP RNA | polymer | 299 | 96826.3 | 1 | GenBank (577019609) | Canis lupus familiaris | |
| 2 | B (2) | tRNA | polymer | 76 | 24437.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 3 | C (3) | Ribosomal protein eL28 | polymer | 125 | 14301.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 4 | D (4) | Ribosomal protein L12 | polymer | 163 | 17689.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 5 | E (5) | 28S ribosomal RNA | polymer | 3658 | 1185357.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 6 | F (6) | 60S acidic ribosomal protein P0 | polymer | 202 | 22217.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 7 | G (7) | 5S ribosomal RNA | polymer | 120 | 38691.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 8 | H (8) | 5.8S ribosomal RNA | polymer | 156 | 50143.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 9 | I (A) | Ribosomal protein L8 | polymer | 244 | 26570.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 10 | J (B) | Ribosomal protein uL3 | polymer | 394 | 44759.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 11 | K (C) | Ribosomal protein uL4 | polymer | 367 | 41635.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 12 | L (D) | Ribosomal protein uL18 | polymer | 292 | 33942.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 13 | M (E) | Ribosomal protein eL6 | polymer | 236 | 27052.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 14 | N (F) | Ribosomal protein uL30 | polymer | 225 | 26590.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 15 | O (G) | Ribosomal protein eL8 | polymer | 238 | 27258.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 16 | P (H) | Ribosomal protein uL6 | polymer | 190 | 21655.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 17 | Q (I) | Ribosomal protein uL16 | polymer | 213 | 24465.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 18 | R (J) | Ribosomal protein uL5 | polymer | 170 | 19359.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 19 | S (L) | Ribosomal protein eL13 | polymer | 210 | 24234.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 20 | T (M) | Ribosomal protein eL14 | polymer | 138 | 16129.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 21 | U (N) | Ribosomal protein L15 | polymer | 203 | 24076.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 22 | V (O) | Ribosomal protein uL13 | polymer | 201 | 23435.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 23 | W (P) | Ribosomal protein uL22 | polymer | 153 | 17757.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 24 | X (Q) | Ribosomal protein eL18 | polymer | 187 | 21457.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 25 | Y (R) | Ribosomal protein eL19 | polymer | 180 | 21613.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 26 | Z (S) | Ribosomal protein eL20 | polymer | 175 | 20696.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 27 | AA (T) | Ribosomal protein eL21 | polymer | 159 | 18478.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 28 | BA (U) | Ribosomal protein eL22 | polymer | 99 | 11481.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 29 | CA (V) | Ribosomal protein L23 | polymer | 131 | 13972.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 30 | DA (W) | Ribosomal protein eL24 | polymer | 63 | 7512.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 31 | EA (X) | Ribosomal protein uL23 | polymer | 119 | 13856.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 32 | FA (Y) | Ribosomal protein uL24 | polymer | 134 | 15891.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 33 | GA (Z) | 60S ribosomal protein L27 | polymer | 135 | 15704.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 34 | HA (a) | Ribosomal protein uL15 | polymer | 147 | 16503.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 35 | IA (b) | 60S ribosomal protein L29 | polymer | 75 | 8722.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 36 | JA (c) | Ribosomal protein eL30 | polymer | 94 | 10496.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 37 | KA (d) | Ribosomal protein eL31 | polymer | 107 | 12635.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 38 | LA (e) | Ribosomal protein eL32 | polymer | 128 | 15022.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 39 | MA (f) | Ribosomal protein eL33 | polymer | 109 | 12433.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 40 | NA (g) | Ribosomal protein eL34 | polymer | 114 | 12994.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 41 | OA (h) | Ribosomal protein uL29 | polymer | 122 | 14460.5 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 42 | PA (i) | Ribosomal protein eL36 | polymer | 102 | 11915.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 43 | QA (j) | Ribosomal protein L37 | polymer | 86 | 10102.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 44 | RA (k) | Ribosomal protein eL38 | polymer | 69 | 8107.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 45 | SA (l) | Ribosomal protein eL39 | polymer | 50 | 6295.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 46 | TA (m) | Ribosomal protein eL40 | polymer | 52 | 6199.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 47 | UA (n) | Ribosomal protein eL41 | polymer | 23 | 3213.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 48 | VA (o) | Ribosomal protein eL42 | polymer | 104 | 12198.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 49 | WA (p) | Ribosomal protein eL43 | polymer | 91 | 10168.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 50 | XA (q) | Signal recognition particle subunit SRP19 | polymer | 105 | 12159.2 | 1 | UniProt (J9PAS6) Pfam (PF01922) | Canis lupus familiaris (Dog) | |
| 51 | YA (r) | Signal recognition particle subunit SRP72,Signal recognition particle subunit SRP72,Signal recognition particle subunit SRP72 | polymer | 605 | 67314.9 | 1 | UniProt (P33731) Pfam (PF17004) Pfam (PF13181) Pfam (PF08492) | Canis lupus familiaris (Dog) | SRP72,Signal recognition particle 72 kDa protein,SRP72,Signal recognition particle 72 kDa protein |
| 52 | ZA (t) | Signal sequence | polymer | 11 | 1262.8 | 1 | Saccharomyces cerevisiae (baker's yeast) | ||
| 53 | AB (u) | Signal recognition particle subunit SRP68 | polymer | 568 | 65570.0 | 1 | UniProt (Q00004) Pfam (PF16969) | Canis lupus familiaris (Dog) | SRP68,Signal recognition particle 68 kDa protein |
| 54 | BB (v) | SRP receptor beta subunit | polymer | 213 | 23588.0 | 1 | UniProt (G1STG2) Pfam (PF09439) | Oryctolagus cuniculus (Rabbit) | |
| 55 | CB (w) | Signal recognition particle 9 kDa protein | polymer | 74 | 8694.1 | 1 | UniProt (P21262) Pfam (PF05486) | Canis lupus familiaris (Dog) | SRP9 |
| 56 | DB (x) | Signal recognition particle 54 kDa protein | polymer | 504 | 55775.7 | 1 | UniProt (P61010) Pfam (PF02978) Pfam (PF02881) Pfam (PF00448) | Canis lupus familiaris (Dog) | SRP54 |
| 57 | EB (y) | SRP receptor alpha subunit | polymer | 657 | 72232.6 | 1 | UniProt (G1TCX6) Pfam (PF04086) Pfam (PF02881) Pfam (PF00448) | Oryctolagus cuniculus (Rabbit) | |
| 58 | FB (z) | Signal recognition particle 14 kDa protein | polymer | 110 | 12512.7 | 1 | UniProt (P16255) Pfam (PF02290) | Canis lupus familiaris (Dog) | SRP14 |
| 59 | AC, AD, AE, AF, AG... (5, 8, P, V, v...) | MAGNESIUM ION | non-polymer | 24.3 | 133 | Chemie (MG) | |||
| 60 | GG, HG, IG (j, m, o) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 61 | KG (v) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 62 | LG, NG (x, y) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 2 | Chemie (GNP) |
Sequence modifications
r: 1 - 581 (UniProt: P33731)
r: 582 - 605 (PDB: 6FRK)
v: 60 - 271 (UniProt: G1STG2)
y: 1 - 637 (UniProt: G1TCX6)
r: 582 - 605 (PDB: 6FRK)
v: 60 - 271 (UniProt: G1STG2)
| PDB | External Database | Details |
|---|---|---|
| Met 59 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| His -17 | - | expression tag |
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Tyr -12 | - | expression tag |
| Asp -11 | - | expression tag |
| Ile -10 | - | expression tag |
| Pro -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 58 |
| Total formula weight | 2499831.3 | |
| Non-Polymers* | Number of molecules | 139 |
| Total formula weight | 4996.4 | |
| All* | Total formula weight | 2504827.7 |
