6FQJ

GluA2(flop) G724C ligand binding core dimer bound to ZK200775 at 2.50 Angstrom resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Glutamate receptor 2,Glutamate receptor 2	polymer	264	29324.8	8	UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2	A, B, C, D, E...	{[7-morpholin-4-yl-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl]methyl}phosphonic acid	non-polymer		409.3	8	Chemie (ZK1)
3		water	water		18.0	825	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 3 - 117 (UniProt: P19491)

PDB	External Database	Details
Gly 1	-	expression tag
Ala 2	-	expression tag

A, B, C, D, E, F, G, H: 120 - 264 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker
Cys 212	Gly 745	conflict

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	234598.6
Non-Polymers*	Number of molecules	8
	Total formula weight	3274.0
All*	Total formula weight	237872.6

*Water molecules are not included.